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Hereditary spastic paraplegia
May 28, 2020
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Hereditary Spastic Paraplegia (HSP), also known as familial spastic paraplegia or Strümpell-Lorrain syndrome, is a group of inherited disorders characterized by progressive stiffness and contraction (spasticity) and weakness of the leg muscles. HSP primarily affects the upper motor neurons, leading to difficulties in walking and maintaining balance.