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Hirschsprung's disease
Hirschsprung's disease is a condition of the large intestine (colon) that causes difficulty passing stool.
Hirschsprung's disease involves missing nerve cells in the muscles of part or all of the large intestine (colon). Present at birth, it causes difficulty passing stool.
The main symptom is a newborn's failure to have a bowel movement within 48 hours after birth. Other symptoms include a swollen stomach and vomiting.
Surgery is required to bypass the affected part of the colon or remove it entirely.