PHARMACOLOGICAL CLASSIFICATION: A 5.8 Preparations for the common cold including decongestants and antihistaminics.
PHARMACOLOGICAL ACTION: FLUSIN SINUS SYRUP has antihistaminic and decongestant properties.
INDICATIONS: The symptomatic relief of mucosal congestion of the upper respiratory tract associated with colds and influenza.
CONTRA-INDICATIONS: Hypersensitivity to any of the ingredients. FLUSIN SINUS SYRUP should not be administered to patients suffering from cardiovascular disease (especially coronary insufficiency),hypertension, prostatism thyrotoxicosis, bladder dysfunction, closed angle glaucoma, phaeochromocytoma and during an attack of asthma inasthmatic patients. Patients being treated with monoamine oxidase inhibitors and within two weeks of stopping such treatment, ephedrine and other sympathomimetic agents as a hypertensive response may result. Safety in pregnancy and lactation has not been established. FLUSIN SINUS SYRUP is contra-indicated in children under two years of age.
WARNINGS: FLUSIN SINUS SYRUP may lead to drowsiness and impaired concentration, which may be aggravated by the simultaneous intake of alcohol or other centralnervous system depressant agents. Patients should not drive, climb dangerous heights or operate machinery as impaired decision-making could lead to accidents. Pseudoephedrine should be given with caution to patients with organic heart disease, cardiac decompensation or angina of effort and in patients receiving digitalis. Do not use this product without consulting a doctor or pharmacist if you are presently taking monoamine oxidase inhibitors or other medicines for depression, psychiatric or emotional conditions or hypertension.
DOSAGE AND DIRECTIONS FOR USE: Adults and children over 12 years: 5-10 mL. Children 6 - 12 years: 5 mL Children 2 - 6 years: 2,5 mL May be given three times daily Not recommended for children under 2 years of age.
SIDE-EFFECTS AND SPECIAL PRECAUTIONS: SIDE-EFFECTS Triprolidine The side-effects of triprolidine include sedation varying from drowsiness to deep sleep, and including lassitude, dizziness and inco-ordination. Paradoxical stimulation may occur particularly in children, with insomnia, nervousness, euphoria, irritability, tremors, and rarely, nightmares, hallucinations and convulsions. Other effects include dry mouth, thickened respiratory tract secretions and tightness of the chest, blurred vision, urinary difficulty and retention, a reduction in tone and motility of the gastro-intestinal tract resulting in constipation and increased gastric reflux, in high doses, transient bradycardia followed by tachycardia with palpitations and arrhythmias; hypotension, tinnitus, headaches and paraesthesias. Other gastro-intestinal disturbances include nausea, vomiting, diarrhoea and epigastric pain. Blood disorders include agranulocytosis, leucopenia, haemolytic anaemia and thrombocytopenia. Pseudoephedrine Central effects include fear, anxiety, restlessness, tremor, insomnia, confusion, irritability and psychotic states. Appetite may be reduced, andnausea and vomiting may occur. Cardiovascular effects include hypertension which may produce cerebral haemorrhage and pulmonary oedema and reflex bradycardia. Tachycardia, cardiac arrhythmias, angina pain, palpitations, cardiac arrest, and hypotension with dizziness and fainting, and flushing may alsooccur. Other side-effects include: difficulty in micturition and urinary retention, dyspnoea, weakness, altered metabolism including disturbances of glucose metabolism,sweating and hypersalivation, and headache.
SPECIAL PRECAUTIONS Triprolidine Should not be given to premature infants or neonates. Should be used with care in the elderly who are more susceptible to many of the side-effects, patients with closed angle glaucoma, urinary retention, prostatic hypertrophy or pyloro-duodenal obstruction, epilepsy, severe cardiovascular disorders. Should not drive or operate machinery. Should avoid alcoholic drinks. Pseudoephedrine Special care should be taken in patients with hyperthyroidism, cardiovascular disease such as ischaemic heart disease, arrhythmia or tachycardia, occlusive vascular disorders including arteriosclerosis, hypertension and aneurysms. Anginal pain may be precipitated in patients with angina pectoris. Diabetes mellitus and closed-angle glaucoma.
INTERACTIONS: Pseudoephedrine Pseudoephedrine should be avoided or used with caution in patients undergoing anaesthesia with cyclopropane, halothane or other halogenated anaesthetics, as they may induce ventricular fibrillation. An increased risk of arrhythmias also occurs if given with cardiac glycosides, quinidine or tricyclic antidepressants. Interaction with monoamine oxidase inhibitors and should not be given to patients receiving such treatment or within 14 days of its termination. Pseudoephedrine increases blood pressure and therefore special care is advised in patients receiving antihypertensive therapy.
KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT: Triprolidine Overdosage may be fatal especially in infants and children. In infants and children, CNS excitement predominates with ataxia, excitement, tremors, psychoses, hallucinations and convulsions; hyperpyrexia may also occur. Deepening coma and respiratory collapse may follow. In adults, CNS depression is more common with drowsiness, coma and convulsions, progressing to respiratory failure and possibly cardiovascular collapse. The stomach should be emptied. Emetics may be tried if the patient is alert and there is no symptoms of toxicity. Other treatment should besymptomatic and supportive and may include artificial respiration, external cooling and IV fluids.
IDENTIFICATION: A light yellow clear syrupy solution with liquorice odour and taste.
STORAGE INSTRUCTIONS: Store below 25ºC and protect from light. KEEP OUT OF REACH OF CHILDREN.
The ZimSeller website does not contain medical advice. The contents of this website, such as text, graphics, images and other material are intended for informational and educational purposes only and not for the purpose of rendering medical advice. The contents of this website are not intended to substitute for professional medical advice, diagnosis or treatment. Although we take efforts to keep the product information on our website updated, we cannot guarantee that the product information, such as medical ingredients or nutritional compositions stated as part of any product description is the most accurate.
Please consult your GP or physician for personalized medical advice. Always seek the advice of a GP or physician or other qualified healthcare provider with any questions regarding your medical condition. Never disregard or delay seeking professional medical advice or treatment because of something you have read on the ZimSeller website.
Before taking any medications, whether it's prescription or over-the-counter medicines, supplements or herbs, consult your GP or a physician for a thorough evaluation. ZimSeller does not endorse any medications, vitamins or herbs. Your GP or a qualified physician should make a decision based on your medical history and current prescriptions. The medication summaries provided do not include all of the information important for patient use and should not be used as a substitute for professional medical advice. The prescribing physician should be consulted concerning any questions that you may have.
In a medical emergency call 999 immediately. ZimSeller does not recommend or endorse any specific test, physician, product, procedure, opinion or any other information provided on its website. Reliance on any information provided by ZimSeller, ZimSeller employees, others represented on the website by ZimSeller' invitation or other visitors to the website, is solely at your own risk.
Therefore the information about this product, or on this website in general, should not be considered current, complete or exhaustive, nor should you rely on such information to recommend a course of treatment for you or any other individual. Reliance on any information provided on this website is solely at your own risk.